TGF-β2 enhances expression of equine bone marrow-derived mesenchymal stem cell paracrine factors with known associations to tendon healing

TGF-β2 enhances expression of equine bone marrow-derived mesenchymal stem cell paracrine factors with known associations to tendon healing

Abstract Background Mesenchymal stem cells (MSCs) secrete paracrine factors and extracellular matrix proteins that contribute to their ability to support tissue healing and regeneration. Both the transcriptome and the secretome of MSCs can be altered by treating the cells with cytokines, but neither...

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Bibliographic Details
Main Authors: Drew W. Koch, Lauren V. Schnabel, Ilene M. Ellis, Rowan E. Bates, Alix K. Berglund
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cell
Tenocyte
TGF-β
Equine
Tendon
RNA-sequencing
Online Access:https://doi.org/10.1186/s13287-022-03172-9

Internet

https://doi.org/10.1186/s13287-022-03172-9

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