JAK2 V617F-dependent upregulation of PU.1 expression in the peripheral blood of myeloproliferative neoplasm patients.

JAK2 V617F-dependent upregulation of PU.1 expression in the peripheral blood of myeloproliferative neoplasm patients.

Myeloproliferative neoplasms (MPN) are multiple disease entities characterized by clonal expansion of one or more of the myeloid lineages (i.e. granulocytic, erythroid, megakaryocytic and mast cell). JAK2 mutations, such as the common V617F substitution and the less common exon 12 mutations, are fre...

Full description

Bibliographic Details
Main Authors: Tamotsu Irino, Munehiro Uemura, Humitsugu Yamane, Shigeto Umemura, Takahiko Utsumi, Naoki Kakazu, Taku Shirakawa, Mitsuhiro Ito, Takayo Suzuki, Kazuo Kinoshita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3138766?pdf=render

Internet

http://europepmc.org/articles/PMC3138766?pdf=render

Similar Items