Applying Box–Behnken Design for Formulation and Optimization of PLGA-Coffee Nanoparticles and Detecting Enhanced Antioxidant and Anticancer Activities

In an attempt to prove biological activity enhancement upon particle size reduction to the nanoscale, coffee (Cf) was chosen to be formulated into poly(lactic-<i>co</i>-glycolic) acid (PLGA) nanoparticles (NPs) using the single emulsion-solvent evaporation (SE-SE) method via Box–Behnken...

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Bibliographic Details
Main Authors: Nouran S. Sharaf, Amro Shetta, Jailan E. Elhalawani, Wael Mamdouh
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/1/144