Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs

Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs

A major parameter controlling the extent and rate of oral drug absorption is permeability through the lipid bilayer of intestinal epithelial cells. Here, a biomimetic artificial membrane permeability assay (Franz–PAMPA Pampa) was validated using a Franz cells apparatus. Both high and low permeabilit...

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Bibliographic Details
Main Authors: Leonardo de Souza Teixeira, Tatiana Vila Chagas, Antonio Alonso, Isabel Gonzalez-Alvarez, Marival Bermejo, James Polli, Kênnia Rocha Rezende
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
Franz–PAMPA
BCS drugs
biomimetic membrane
Franz cell
passive drug transport
Online Access:https://www.mdpi.com/1999-4923/12/10/988

Internet

https://www.mdpi.com/1999-4923/12/10/988

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