Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma sprucei Hook. f. Isolamento de isobruceina B e neosergeolida de Picrolemma sprucei Hook. f. em escala-grama

Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma sprucei Hook. f. Isolamento de isobruceina B e neosergeolida de Picrolemma sprucei Hook. f. em escala-grama

Quassinoids neosergeolide and isobrucein B, obtained from Picrolemma sprucei, have proven in vitro antitumor, antimalarial, anthelminthic, cytotoxic, insecticide and leishmanicidal activities. There is interest in the in vivo pharmacological study of these natural compounds and their semi-synthetic...

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Bibliographic Details
Main Authors: Ellen Cristina Costa da Silva, Rodrigo César das Neves Amorim, Wanderli Pedro Tadei, Adrian Martin Pohlit
Format: Article
Language:English
Published: Instituto Nacional de Pesquisas da Amazônia 2009-03-01
Series:Acta Amazonica
Subjects:
Caferana
Simaroubaceae
Quassinóide
Recristalização
Quassinoid
Recrystallization
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000100026

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000100026

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