Higher levels of thyroxine may predict a favorable response to donepezil treatment in patients with Alzheimer disease: a prospective, case–control study

Abstract Background Cholinergic hypothesis has been advanced as an etiology of Alzheimer disease (AD) on the basis of the presynaptic deficit found in the diseased brains, and cholinesterase inhibitors (ChEIs) are the treatment of choice for these patients. However, only about half of treatment effi...

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Bibliographic Details
Main Authors: Yu San Chang, Yu Hsuan Wu, Chin Jen Wang, Shu Hui Tang, Hsiang Lan Chen
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Neuroscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12868-018-0436-x