The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic bioactive lipid mediator capable of evoking complex immune phenomena. Studies have highlighted its importance regarding intracellular signaling cascades as well as membrane-bound S1P receptor (S1PR) engagement in va...

Full description

Bibliographic Details
Main Authors: Alexandra Lucaciu, Robert Brunkhorst, Josef M. Pfeilschifter, Waltraud Pfeilschifter, Julien Subburayalu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
sphingosine 1-phoshate
sphingosine 1-phosphate receptor
S1P<sub>1–5</sub>
sphingosine 1-phosphate metabolism
sphingosine 1-phosphate antagonistst/inhibitors
sphingosine 1-phosphate signaling
Online Access:https://www.mdpi.com/2073-4409/9/6/1515

Internet

https://www.mdpi.com/2073-4409/9/6/1515

Similar Items