The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic bioactive lipid mediator capable of evoking complex immune phenomena. Studies have highlighted its importance regarding intracellular signaling cascades as well as membrane-bound S1P receptor (S1PR) engagement in va...

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Bibliographic Details
Main Authors:	Alexandra Lucaciu, Robert Brunkhorst, Josef M. Pfeilschifter, Waltraud Pfeilschifter, Julien Subburayalu
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Series:	Cells
Subjects:	sphingosine 1-phoshate sphingosine 1-phosphate receptor S1P<sub>1–5</sub> sphingosine 1-phosphate metabolism sphingosine 1-phosphate antagonistst/inhibitors sphingosine 1-phosphate signaling
Online Access:	https://www.mdpi.com/2073-4409/9/6/1515

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