Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice

Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice

Abstract Background In recent years, mechanistic, epidemiologic, and interventional studies have indicated beneficial effects of omega-3 polyunsaturated fatty acids (n-3 PUFA) against brain aging and age-related cognitive decline, with the most consistent effects against Alzheimer’s disease (AD) con...

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Bibliographic Details
Main Authors: Debora Cutuli, Eugenia Landolfo, Annalisa Nobili, Paola De Bartolo, Stefano Sacchetti, Doriana Chirico, Federica Marini, Luisa Pieroni, Maurizio Ronci, Marcello D’Amelio, Francesca Romana D’Amato, Stefano Farioli-Vecchioli, Laura Petrosini
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
Aging
Cholinergic system
Omega-3 fatty acids
Memory deficits
Diet
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s13195-020-00705-3

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http://link.springer.com/article/10.1186/s13195-020-00705-3

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