Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells

Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells

Abstract Generation of hematopoietic stem/progenitor cells (HSPCs) via cell expansion or cell reprogramming has been widely achieved by overexpression of transcription factors. Herein, it is reported that without introducing exogenous genes, mouse fibroblasts can be reprogrammed into hemogenic cells...

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Bibliographic Details
Main Authors: Yi Zhou, Xingli Zhu, Yuting Dai, Shumin Xiong, Chuijin Wei, Pei Yu, Yuewen Tang, Liang Wu, Jianfeng Li, Dan Liu, Yanlin Wang, Zhu Chen, Sai‐Juan Chen, Jinyan Huang, Lin Cheng
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Advanced Science
Subjects:
cell expansion
cell fate change
cell reprogramming
chemical cocktails
hematopoietic stem/progenitor cells
Online Access:https://doi.org/10.1002/advs.201901785

Internet

https://doi.org/10.1002/advs.201901785

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