Bacitracin enhances ceftriaxone susceptibility of the high-level ceftriaxone-resistant gonococcal FC428 clone

Bacitracin enhances ceftriaxone susceptibility of the high-level ceftriaxone-resistant gonococcal FC428 clone

ABSTRACT Neisseria gonorrhoeae is a multidrug-resistant bacterial pathogen for which ceftriaxone mono-antimicrobial therapy and ceftriaxone plus azithromycin dual-antimicrobial therapy are the only remaining effective therapies. However, ceftriaxone efficacy is threatened by the global dissemination...

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Bibliographic Details
Main Authors: Yuhua Gu, Shuaijie Song, Qingrui Zhu, Ruilin Jiao, Xu'ai Lin, Fan Yang, Stijn van der Veen
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
Neisseria gonorrhoeae
FC428
bacitracin
ceftriaxone
antimicrobial synergy
FICI
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02449-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02449-23

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