KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity

KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity

ABSTRACT Influenza A virus (IAV) RNA-dependent RNA polymerase (vPol) is a heterotrimer composed of PB2, PB1, and PA, which, together with vRNA and nucleoprotein (NP), forms viral ribonucleoprotein (vRNP) complex to direct the transcription and replication of the viral genome. Host factor ANP32 prote...

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Bibliographic Details
Main Authors: Mengmeng Yu, Liuke Sun, Zhenyu Zhang, Yuan Zhang, Haili Zhang, Lei Na, Xiaojun Wang
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
vRNP
ANP32A
ANP32B
KPNA6
influenza
polymerase
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02073-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02073-21

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