Improved Whole Gamma Irradiated Avian Influenza Subtype H9N2 Virus Vaccine Using Trehalose and Optimization of Vaccination Regime on Broiler Chicken

Improved Whole Gamma Irradiated Avian Influenza Subtype H9N2 Virus Vaccine Using Trehalose and Optimization of Vaccination Regime on Broiler Chicken

Gamma (γ)-radiation can target viral genome replication and preserve viral structural proteins compared to formalin inactivation. Thus, a stronger immunity could be induced after the inoculation of the irradiated virus. In this study, γ-irradiated low-pathogenic avian influenza virus-H9N2 (LPAIV-H9N...

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Bibliographic Details
Main Authors: Farahnaz Motamedi Sedeh, Iraj Khalili, Viskam Wijewardana, Hermann Unger, Parvin Shawrang, Mehdi Behgar, Sayed Morteza Moosavi, Arash Arbabi, Sayedeh Maede Hosseini
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Veterinary Science
Subjects:
avian influenza virus
gamma-radiation
vaccine
immune response
virus shedding
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.907369/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2022.907369/full

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