Recent progress of aptamer‒drug conjugates in cancer therapy

Recent progress of aptamer‒drug conjugates in cancer therapy

Aptamers are single-stranded DNA or RNA sequences that can specifically bind with the target protein or molecule via specific secondary structures. Compared to antibody-drug conjugates (ADC), aptamer‒drug conjugate (ApDC) is also an efficient, targeted drug for cancer therapy with a smaller size, hi...

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Bibliographic Details
Main Authors: Jiaxuan He, Qiao Duan, Chunyan Ran, Ting Fu, Yuan Liu, Weihong Tan
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Aptamer
Cancer therapy
Aptamer‒drug conjugate
Drug delivery
Small-molecule drug
Therapeutic molecules
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523000175

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http://www.sciencedirect.com/science/article/pii/S2211383523000175

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