BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory

Tuberculosis (TB) is one of the leading causes of death due to infectious disease. The sole established vaccine against TB is the Mycobacterium bovis Bacillus Calmette–Guerin (BCG) vaccine. However, owing to the lack of durable immunity with the BCG vaccine and its risk of infection, safer vaccines...

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Main Authors: Takehiro Yamaguchi, Noriaki Samukawa, Sohkichi Matsumoto, Masayuki Shiota, Masaki Matsumoto, Ryoma Nakao, Satoru Hirayama, Yutaka Yoshida, Akihito Nishiyama, Yuriko Ozeki, Shuhei Tomita
格式: 文件
语言:English
出版: Frontiers Media S.A. 2025-03-01
丛编:Frontiers in Immunology
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在线阅读:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1534615/full