African-American esophageal squamous cell carcinoma expression profile reveals dysregulation of stress response and detox networks

African-American esophageal squamous cell carcinoma expression profile reveals dysregulation of stress response and detox networks

Abstract Background Esophageal carcinoma is the third most common gastrointestinal malignancy worldwide and is largely unresponsive to therapy. African-Americans have an increased risk for esophageal squamous cell carcinoma (ESCC), the subtype that shows marked variation in geographic frequency. The...

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Bibliographic Details
Main Authors: Hayriye Verda Erkizan, Kory Johnson, Svetlana Ghimbovschi, Deepa Karkera, Gregory Trachiotis, Houtan Adib, Eric P. Hoffman, Robert G. Wadleigh
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Cancer
Subjects:
mRNA expression
Microarray
Down-regulated genes
Up-regulated genes
Pathway analysis
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s12885-017-3423-1

Internet

http://link.springer.com/article/10.1186/s12885-017-3423-1

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