A cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy

Abstract Physiological rapid eye movement (REM) sleep termination is vital for initiating non-REM (NREM) sleep or arousal, whereas the suppression of excessive REM sleep is promising in treating narcolepsy. However, the neuronal mechanisms controlling REM sleep termination and keeping sleep continua...

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Bibliographic Details
Main Authors: Ze-Ka Chen, Hui Dong, Cheng-Wei Liu, Wen-Ying Liu, Ya-Nan Zhao, Wei Xu, Xiao Sun, Yan-Yu Xiong, Yuan-Yuan Liu, Xiang-Shan Yuan, Bing Wang, Michael Lazarus, Yoan Chérasse, Ya-Dong Li, Fang Han, Wei-Min Qu, Feng-Fei Ding, Zhi-Li Huang
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00456-5