Female rats have a different healing phenotype than males after anterior cruciate ligament rupture with no intervention

Little is known on the sex-specific healing responses after an anterior cruciate ligament (ACL) rupture. To address this, we compared male and female Sprague-Dawley rats following non-surgical ACL rupture. Hematology, inflammation, joint swelling, range of motion, and pain-sensitivity were analyzed...

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Bibliographic Details
Main Authors: Jodie L. Morris, Hayley L. Letson, Erik Biros, Peter C. McEwen, Geoffrey P. Dobson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.976980/full