The impact of single nucleotide polymorphisms in MTHFR and MTRR genes on disease activity and the presence of methotrexate treatment side effects in children with juvenile idiopathic arthritis

The impact of single nucleotide polymorphisms in MTHFR and MTRR genes on disease activity and the presence of methotrexate treatment side effects in children with juvenile idiopathic arthritis

Introduction To determine the impact of single nucleotide polymorphisms (SNPs) in MTHFR and MTRR genes on disease activity and the presence of MTX therapy adverse events in Polish children with juvenile idiopathic arthritis (JIA). Material and methods SNP genotyping was performed using genomic DNA...

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Bibliographic Details
Main Authors: Justyna Roszkiewicz, Dominika Michałek, Aleksandra Ryk, Bartosz Szmyd, Elzbieta Smolewska
Format: Article
Language:English
Published: Termedia Publishing House 2023-05-01
Series:Archives of Medical Science
Subjects:
methotrexate
pharmacogenomics
single nucleotide polymorphism
juvenile idiopathic arthritis
Online Access:https://www.archivesofmedicalscience.com/The-impact-of-single-nucleotide-polymorphisms-in-MTHFR-and-MTRR-genes-on-disease,163259,0,2.html

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https://www.archivesofmedicalscience.com/The-impact-of-single-nucleotide-polymorphisms-in-MTHFR-and-MTRR-genes-on-disease,163259,0,2.html

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