Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K<sup>+</sup> Channel Subunits Kv8.2 and K2.1

Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K<sup>+</sup> Channel Subunits Kv8.2 and K2.1

Cone Dystrophy with Supernormal Rod Response (CDSRR) is a rare autosomal recessive disorder leading to severe visual impairment in humans, but little is known about its unique pathophysiology. We have previously shown that CDSRR is caused by mutations in the <i>KCNV2</i> (Potassium Volta...

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Bibliographic Details
Main Authors: Xiaotian Jiang, Rabab Rashwan, Valentina Voigt, Jeanne Nerbonne, David M. Hunt, Livia S. Carvalho
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
CDSRR
cone-rod dystrophy
<i>KCNV2</i>
<i>KCNB1</i>
voltage-gated potassium channels
photoreceptors
Online Access:https://www.mdpi.com/1422-0067/22/9/4877

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https://www.mdpi.com/1422-0067/22/9/4877

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