Induction of IL-9 in Peripheral Lymphocytes of Rheumatoid Arthritis Patients and Healthy Donors by Th17-Inducing Cytokine Conditions

Induction of IL-9 in Peripheral Lymphocytes of Rheumatoid Arthritis Patients and Healthy Donors by Th17-Inducing Cytokine Conditions

IL-9-producing Th9 cells display a group of helper T cells with similarities to Th17 and Th2 T cells and have been shown to be involved in synovial inflammation in rheumatoid arthritis (RA) patients. So far, it is unclear which parameters drive Th9 differentiation in lymphocytes derived from RA pati...

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Bibliographic Details
Main Authors: Jana Heim, Giovanni Almanzar, Marc Schmalzing, Michael Gernert, Hans-Peter Tony, Martina Prelog
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
Th9
Th17
interleukin-9
rheumatoid arthritis
PU.1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.668095/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.668095/full

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