Berberine Targets PKM2 to Activate the t-PA-Induced Fibrinolytic System and Improves Thrombosis

Berberine Targets PKM2 to Activate the t-PA-Induced Fibrinolytic System and Improves Thrombosis

Background: Arterial thrombosis, a condition in which thrombi form in arteries, can lead to various acute cardiovascular diseases and impact the quality of life and survival of patients. Berberine (BBR), a quaternary ammonium alkaloid, has been shown to treat these diseases. However, further explora...

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Bibliographic Details
Main Authors: Zeqi Sun, Tong Zhao, Xue Bai, Huimin Li, Jin Gao, Yutong Hao, Yiyang Li, Yanli Xie, Ange Hu, Qiang Huang, Xin Liu, Yong Zhang
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Pharmaceuticals
Subjects:
berberine
PKM2
t-PA
fibrinolytic system
thrombosis
Online Access:https://www.mdpi.com/1424-8247/17/9/1219

Internet

https://www.mdpi.com/1424-8247/17/9/1219

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