Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells

The precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implant...

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Bibliographic Details
Main Authors: Shaopeng Zhang, Tianzhi Chen, Naixin Chen, Dengfeng Gao, Bingbo Shi, Shuangbo Kong, Rachel Claire West, Ye Yuan, Minglei Zhi, Qingqing Wei, Jinzhu Xiang, Haiyuan Mu, Liang Yue, Xiaohua Lei, Xuepeng Wang, Liang Zhong, Hui Liang, Suying Cao, Juan Carlos Izpisua Belmonte, Haibin Wang, Jianyong Han
Format: Article
Language:English
Published: Nature Portfolio 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08378-9

Internet

https://doi.org/10.1038/s41467-019-08378-9

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