Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells
The precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implant...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-08378-9 |
| _version_ | 1818834969724715008 |
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| author | Shaopeng Zhang Tianzhi Chen Naixin Chen Dengfeng Gao Bingbo Shi Shuangbo Kong Rachel Claire West Ye Yuan Minglei Zhi Qingqing Wei Jinzhu Xiang Haiyuan Mu Liang Yue Xiaohua Lei Xuepeng Wang Liang Zhong Hui Liang Suying Cao Juan Carlos Izpisua Belmonte Haibin Wang Jianyong Han |
| author_facet | Shaopeng Zhang Tianzhi Chen Naixin Chen Dengfeng Gao Bingbo Shi Shuangbo Kong Rachel Claire West Ye Yuan Minglei Zhi Qingqing Wei Jinzhu Xiang Haiyuan Mu Liang Yue Xiaohua Lei Xuepeng Wang Liang Zhong Hui Liang Suying Cao Juan Carlos Izpisua Belmonte Haibin Wang Jianyong Han |
| author_sort | Shaopeng Zhang |
| collection | DOAJ |
| description | The precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implantation response. |
| first_indexed | 2024-12-19T02:43:16Z |
| format | Article |
| id | doaj.art-7ac0b1da37484bc9a2f0c73efcf90ab1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T02:43:16Z |
| publishDate | 2019-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-7ac0b1da37484bc9a2f0c73efcf90ab12022-12-21T20:39:03ZengNature PortfolioNature Communications2041-17232019-01-0110111710.1038/s41467-019-08378-9Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cellsShaopeng Zhang0Tianzhi Chen1Naixin Chen2Dengfeng Gao3Bingbo Shi4Shuangbo Kong5Rachel Claire West6Ye Yuan7Minglei Zhi8Qingqing Wei9Jinzhu Xiang10Haiyuan Mu11Liang Yue12Xiaohua Lei13Xuepeng Wang14Liang Zhong15Hui Liang16Suying Cao17Juan Carlos Izpisua Belmonte18Haibin Wang19Jianyong Han20State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityFujian Provincial Key Laboratory of Reproductive Health Research, Medical College of Xiamen UniversityColorado Center for Reproductive MedicineColorado Center for Reproductive MedicineState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of SciencesState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of SciencesCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of SciencesState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityAnimal Science and Technology College, Beijing University of AgricultureSalk Institute for Biological StudiesFujian Provincial Key Laboratory of Reproductive Health Research, Medical College of Xiamen UniversityState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural UniversityThe precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implantation response.https://doi.org/10.1038/s41467-019-08378-9 |
| spellingShingle | Shaopeng Zhang Tianzhi Chen Naixin Chen Dengfeng Gao Bingbo Shi Shuangbo Kong Rachel Claire West Ye Yuan Minglei Zhi Qingqing Wei Jinzhu Xiang Haiyuan Mu Liang Yue Xiaohua Lei Xuepeng Wang Liang Zhong Hui Liang Suying Cao Juan Carlos Izpisua Belmonte Haibin Wang Jianyong Han Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells Nature Communications |
| title | Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells |
| title_full | Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells |
| title_fullStr | Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells |
| title_full_unstemmed | Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells |
| title_short | Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells |
| title_sort | implantation initiation of self assembled embryo like structures generated using three types of mouse blastocyst derived stem cells |
| url | https://doi.org/10.1038/s41467-019-08378-9 |
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