Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells
The precise cellular patterning and decisions of early embryogenesis have been hard to mimic in vitro. Here, the authors culture murine embryonic and trophoblast stem cells together with extra-embryonic endoderm stem cells to form embryo-like structures (ETX-embryoids), which can initiate an implant...
Main Authors: | Shaopeng Zhang, Tianzhi Chen, Naixin Chen, Dengfeng Gao, Bingbo Shi, Shuangbo Kong, Rachel Claire West, Ye Yuan, Minglei Zhi, Qingqing Wei, Jinzhu Xiang, Haiyuan Mu, Liang Yue, Xiaohua Lei, Xuepeng Wang, Liang Zhong, Hui Liang, Suying Cao, Juan Carlos Izpisua Belmonte, Haibin Wang, Jianyong Han |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-08378-9 |
Similar Items
-
Pluripotent stem cells secrete Activin A to improve their epiblast competency after injection into recipient embryos
by: Jinzhu Xiang, et al.
Published: (2017-10-01) -
IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells
by: Bingbo Shi, et al.
Published: (2020-11-01) -
Day 3 Embryo Morphology is a Significant Predictor of Blastocyst Euploidy
by: Yunhao Liang, et al.
Published: (2023-11-01) -
Protocol for the generation of blastocyst-like structures from mouse extended pluripotent stem cells
by: Ronghui Li, et al.
Published: (2021-09-01) -
Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos
by: Wei Zheng, et al.
Published: (2021-11-01)