Effect of Date Palm (Phoenix dactylifera) Phytochemicals on Aβ1−40 Amyloid Formation: An in-silico Analysis

Effect of Date Palm (Phoenix dactylifera) Phytochemicals on Aβ1−40 Amyloid Formation: An in-silico Analysis

Alzheimer's disease (AD) is a neurodegenerative disease and the most prevalent form of dementia. The generation of oxygen free radicals and oxidative damage is believed to be involved in the pathogenesis of AD. It has been suggested that date palm, a plant rich in phenolic compounds and flavono...

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Main Authors: Qamar Zia, Md Tabish Rehman, Md Amiruddin Hashmi, Sahabjada Siddiqui, Abdulaziz Bin Dukhyil, Mohammad Z. Ahmed, Azfar Jamal, Saeed Banawas, Sami G. Almalki, Mohammad Owais, Hamad Qasem Aldhafeeri, Ibrahim M. Ibrahim, Wael Alturaiki, Mohamed F. AlAjmi, Mohammed Alsieni, Yaser E. Alqurashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer's disease
Phoenix dactylifera (date palm)
molecular docking (MD)
phytochemicals (alkaloids/lignans)
drug likeness and bioactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.915122/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.915122/full

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