TRIM21 deficiency protects against atrial inflammation and remodeling post myocardial infarction by attenuating oxidative stress

TRIM21 deficiency protects against atrial inflammation and remodeling post myocardial infarction by attenuating oxidative stress

Atrial remodeling is a major contributor to the onset of atrial fibrillation (AF) after myocardial infarction (MI). Tripartite motif-containing protein 21 (TRIM21), an E3 ubiquitin protein ligase, is associated with pathological cardiac remodeling and dysfunction. However, the role of TRIM21 in post...

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Bibliographic Details
Main Authors: Xiangdong Liu, Wenming Zhang, Jiachen Luo, Wentao Shi, Xingxu Zhang, Zhiqiang Li, Xiaoming Qin, Baoxin Liu, Yidong Wei
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Subjects:
Tripartite motif-containing protein 21
Myocardial infarction
Oxidative stress
Inflammation
Nuclear factor kappa B
NADPH oxidase 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723000800

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http://www.sciencedirect.com/science/article/pii/S2213231723000800

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