Enhancing Solid-Phase Extraction of Tamoxifen and Its Metabolites from Human Plasma Using MOF-Integrated Polyacrylonitrile Composites: A Study on CuBTC and ZIF-8 Efficacy

Enhancing Solid-Phase Extraction of Tamoxifen and Its Metabolites from Human Plasma Using MOF-Integrated Polyacrylonitrile Composites: A Study on CuBTC and ZIF-8 Efficacy

This study investigates electrospun fibers of metal-organic frameworks (MOFs), particularly CuBTC and ZIF-8, in polyacrylonitrile (PAN) for the solid-phase extraction (SPE) of Tamoxifen (TAM) and its metabolites (NDTAM, ENDO, and 4OHT) from human blood plasma. The focus is on the isolation, pre-conc...

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Bibliographic Details
Main Authors: Domingo R. Flores-Hernandez, Héctor Manuel Leija Gutiérrez, Jose A. Hernandez-Hernandez, José Antonio Sánchez-Fernández, Jaime Bonilla-Rios
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Nanomaterials
Subjects:
metal organic frameworks
MOF
nanocomposite
tamoxifen
nanofibers
electrospinning
Online Access:https://www.mdpi.com/2079-4991/14/1/73

Internet

https://www.mdpi.com/2079-4991/14/1/73

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