Persistent expression of hepatitis C virus non-structural proteins leads to increased autophagy and mitochondrial injury in human hepatoma cells.

Persistent expression of hepatitis C virus non-structural proteins leads to increased autophagy and mitochondrial injury in human hepatoma cells.

HCV infection is a major cause of chronic liver disease and liver cancer in the United States. To address the pathogenesis caused by HCV infection, recent studies have focused on the direct cytopathic effects of individual HCV proteins, with the objective of identifying their specific roles in the o...

Full description

Bibliographic Details
Main Authors: Victor C Chu, Sayanti Bhattacharya, Ann Nomoto, Jiahui Lin, Syed Kashif Zaidi, Terry D Oberley, Steven A Weinman, Salman Azhar, Ting-Ting Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3229600?pdf=render

Internet

http://europepmc.org/articles/PMC3229600?pdf=render

Similar Items