Comprehensive Understanding of the Kinetic Behaviors of Main Protease from SARS-CoV-2 and SARS-CoV: New Data and Comparison to Published Parameters

The main protease (M<sup>pro</sup>) is a promising drug target for inhibiting the coronavirus due to its conserved properties and lack of homologous genes in humans. However, previous studies on M<sup>pro</sup>’s kinetic parameters have been confusing, hindering the selection...

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Bibliographic Details
Main Authors: Fangya Li, Tingting Fang, Feng Guo, Zipeng Zhao, Jianyu Zhang
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/12/4605