Noise management by molecular networks.

Fluctuations in the copy number of key regulatory macromolecules ("noise") may cause physiological heterogeneity in populations of (isogenic) cells. The kinetics of processes and their wiring in molecular networks can modulate this molecular noise. Here we present a theoretical framework t...

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Bibliographic Details
Main Authors: Frank J Bruggeman, Nils Blüthgen, Hans V Westerhoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2731877?pdf=render