Steppogenin Isolated from Cudrania tricuspidata Shows Antineuroinflammatory Effects via NF-κB and MAPK Pathways in LPS-Stimulated BV2 and Primary Rat Microglial Cells

Steppogenin Isolated from Cudrania tricuspidata Shows Antineuroinflammatory Effects via NF-κB and MAPK Pathways in LPS-Stimulated BV2 and Primary Rat Microglial Cells

Excessive microglial stimulation has been recognized in several neurodegenerative diseases, including Parkinson’s disease (PD), Alzheimer’s disease (AD), amyotropic lateral sclerosis (ALS), HIV-associated dementia (HAD), multiple sclerosis (MS), and stroke. When microglia are stimulated, they produc...

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Bibliographic Details
Main Authors: Dong-Cheol Kim, Tran Hong Quang, Hyuncheol Oh, Youn-Chul Kim
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
steppogenin
Cudrania tricuspidata
neuroinflammation
nuclear factor-kappa B (NF-κB)
mitogen-activated protein kinase (MAPK)
Online Access:https://www.mdpi.com/1420-3049/22/12/2130

Internet

https://www.mdpi.com/1420-3049/22/12/2130

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