Impact of host IL28B rs12979860, rs8099917 in interferon responsiveness and advanced liver disease in chronic genotype 3 hepatitis C patients.

BACKGROUND AND AIMS:Genetic polymorphisms near interleukin 28B gene are associated with spontaneous and treatment induced clearance of hepatitis C virus (HCV). Our objective was to evaluate the impact of interleukin 28B single nucleotide polymorphism (rs12979860, rs8099917) variability in HCV genoty...

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Bibliographic Details
Main Authors: Rushna Firdaus, Aritra Biswas, Kallol Saha, Anirban Mukherjee, Sujit Chaudhuri, Alok Chandra, Asokananda Konar, Provash Chandra Sadhukhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4051780?pdf=render