PPP1R3A inhibits osteogenesis and negatively regulates intracellular calcium levels in calcific tendinopathy

PPP1R3A inhibits osteogenesis and negatively regulates intracellular calcium levels in calcific tendinopathy

Summary: Calcific tendinopathy (CT) is defined by the progressive accumulation of calcium crystals in tendonic regions that results in severe pain in patients. The etiology of CT is not fully elucidated. In this study, we elucidate the role of PPP1R3A in CT. A significant decrease in PPP1R3A express...

Full description

Bibliographic Details
Main Authors: Chao Hu, Lin Ma, Shang Gao, Ming-Yu Yang, Mi-Duo Mu, Le Chang, Pan Huang, Xiao Ye, Wei Wang, Xu Tao, Bing-Hua Zhou, Wan Chen, Kang-Lai Tang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Orthopedics
Molecular biology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018618

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223018618

Similar Items