Long-term alteration of intestinal microbiota in patients with ulcerative colitis by antibiotic combination therapy.

Previous work has demonstrated that intestinal bacteria, such as Fusobacterium varium (F. varium), contribute to the clinical activity in ulcerative colitis (UC); thus, an antibiotic combination therapy (amoxicillin, tetracycline, and metronidazole (ATM)) against F. varium can induce and maintain UC...

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Main Authors: Shigeo Koido, Toshifumi Ohkusa, Takayuki Kajiura, Junko Shinozaki, Manabu Suzuki, Keisuke Saito, Kazuki Takakura, Shintaro Tsukinaga, Shunichi Odahara, Toyokazu Yukawa, Jimi Mitobe, Mikio Kajihara, Kan Uchiyama, Hiroshi Arakawa, Hisao Tajiri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906066?pdf=render