Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone

Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone

Objectives Ochronotic spondyloarthropathy represents one of the main clinical manifestations of alkaptonuria (AKU); however, prospective data and description of the effect of nitisinone treatment are lacking.Methods Patients with AKU aged 25 years or older were randomly assigned to receive either or...

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Bibliographic Details
Main Authors: Lakshminarayan R Ranganath, Milad Khedr, Jean-Baptiste Arnoux, Jozef Rovensky, Richard Jackson, Vanda Mlynarikova, Helen Bygott, Birgitta Olsson, Mattias Rudebeck, Andrea Zatkova, Richard Imrich, Olga Lukacova, Jana Sedlakova, Mária Úlehlová, Matthew Gornall, James Gallagher, Roman Stančík, Eva Vrtíková, Elizabeth Záňová, Emily Luangrath
Format: Article
Language:English
Published: BMJ Publishing Group 2022-10-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/8/2/e002422.full

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https://rmdopen.bmj.com/content/8/2/e002422.full

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