Mechanisms of PKA-Dependent Potentiation of Kv7.5 Channel Activity in Human Airway Smooth Muscle Cells

Mechanisms of PKA-Dependent Potentiation of Kv7.5 Channel Activity in Human Airway Smooth Muscle Cells

β-adrenergic receptor (βAR) activation promotes relaxation of both vascular and airway smooth muscle cells (VSMCs and ASMCs, respectively), though the signaling mechanisms have not been fully elucidated. We previously found that the activity of Kv7.5 voltage-activated potassium cha...

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Bibliographic Details
Main Authors: Lyubov I. Brueggemann, Leanne L. Cribbs, Jeffrey Schwartz, Minhua Wang, Ahmed Kouta, Kenneth L. Byron
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
smooth muscle
β-adrenergic receptor
Kv7 voltage-activated potassium channel
protein kinase A
Online Access:http://www.mdpi.com/1422-0067/19/8/2223

Internet

http://www.mdpi.com/1422-0067/19/8/2223

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