Modeling and inferring cleavage patterns in proliferating epithelia.

The regulation of cleavage plane orientation is one of the key mechanisms driving epithelial morphogenesis. Still, many aspects of the relationship between local cleavage patterns and tissue-level properties remain poorly understood. Here we develop a topological model that simulates the dynamics of...

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Bibliographic Details
Main Authors: Ankit B Patel, William T Gibson, Matthew C Gibson, Radhika Nagpal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2688032?pdf=render