Spatial adjustment of bioenergetics, a possible determinant of contractile adaptation and development of contractile failure

Cardiomyocytes depend on mitochondrial oxidative phosphorylation (OXPHOS) for energy metabolism, which is facilitated by the mitochondrial electron transfer system (ETS). In a series of thermogenic redox reactions, electrons are shuttled through the ETS to oxygen as the final electron acceptor. This...

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Bibliographic Details
Main Authors: Marten Szibor, Marie Mühlon, Torsten Doenst, Jaakko L. O. Pohjoismäki
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Molecular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmmed.2023.1305960/full