Spatial adjustment of bioenergetics, a possible determinant of contractile adaptation and development of contractile failure
Cardiomyocytes depend on mitochondrial oxidative phosphorylation (OXPHOS) for energy metabolism, which is facilitated by the mitochondrial electron transfer system (ETS). In a series of thermogenic redox reactions, electrons are shuttled through the ETS to oxygen as the final electron acceptor. This...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-12-01
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Series: | Frontiers in Molecular Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmmed.2023.1305960/full |