Saponins from Panax japonicus attenuate age-related neuroinflammation via regulation of the mitogen-activated protein kinase and nuclear factor kappa B signaling pathways

Saponins from Panax japonicus attenuate age-related neuroinflammation via regulation of the mitogen-activated protein kinase and nuclear factor kappa B signaling pathways

Neuroinflammation is recognized as an important pathogenic factor for aging and related cognitive disorders. Mitogen-activated protein kinase and nuclear factor kappa B signaling pathways may mediate neuroinflammation. Saponins from Panax japonicus are the most abundant and bioactive members in rhiz...

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Bibliographic Details
Main Authors: Li-li Deng, Ding Yuan, Zhi-yong Zhou, Jing-zhi Wan, Chang-cheng Zhang, Chao-qi Liu, Yao-yan Dun, Hai-xia Zhao, Bo Zhao, Yuan-jian Yang, Ting Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; saponins from Panax japonicus; aging; neuroinflammation; microglia; inflammatory factor; mitogen-activated protein kinase; nuclear factor kappa B; extracellular signal-regulated kinase; c-Jun N-terminal kinase; p38; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=11;spage=1877;epage=1884;aulast=Deng

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=11;spage=1877;epage=1884;aulast=Deng

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