Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer

Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer

The treatment of cancer mainly involves surgical excision supplemented by radiotherapy and chemotherapy. Chemotherapy drugs act by interfering with tumor growth and inducing the death of cancer cells. Anti-tumor drugs were developed to induce apoptosis, but some patient’s show apoptosis escape and c...

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Bibliographic Details
Main Authors: Feifei Pu, Fengxia Chen, Zhicai Zhang, Deyao Shi, Binlong Zhong, Xiao Lv, Andrew Blake Tucker, Jiaming Fan, Alexander J. Li, Kevin Qin, Daniel Hu, Connie Chen, Hao Wang, Fang He, Na Ni, Linjuan Huang, Qing Liu, William Wagstaff, Hue H. Luu, Rex C. Haydon, Le Shen, Tong-Chuan He, Jianxiang Liu, Zengwu Shao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-03-01
Series:Genes and Diseases
Subjects:
Cancer
Cancer therapy
Clinical application
Ferroptosis
Lipid peroxidation
Pathogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301562

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http://www.sciencedirect.com/science/article/pii/S2352304220301562

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