Development and Validation of HPLC-FLD Analysis of Perampanel in MEPS-Processed Rat Plasma Sample

Perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist, is registered for the adjunctive treatment of patients (aged ≥ 12 years) with refractory partial-onset seizures. A simple high-performance liquid chromatographic method fluorescence detection (HPLC-F...

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Bibliographic Details
Main Authors: Ayah Nader Abu-shark, Ashok K. Shakya, Safwan M. Al-Adwan, Rajashri R. Naik
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Separations
Subjects:
Online Access:https://www.mdpi.com/2297-8739/11/2/55