Validation of chromogenic in situ hybridization reactions for DNA and RNA detection in formalin-fixed paraffin-embedded tissue

Validation of chromogenic in situ hybridization reactions for DNA and RNA detection in formalin-fixed paraffin-embedded tissue

ABSTRACT Introduction: Chromogenic in situ hybridization (CISH) is used alternatively to the traditional immunohistochemical methods for the diagnosis of infectious diseases in formalin-fixed paraffin-embedded samples, since it presents high sensitivity and specificity. This type of sample undergoe...

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Bibliographic Details
Main Authors: Raquel L. Monteiro, Daniela S. Damaceno, Lidia M. Kimura, Cinthya S. Cirqueira, Juliana M. Guerra, Leonardo José T. Araújo
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2019-05-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
in situ hybridization
quality control
molecular diagnostic techniques
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000100057&tlng=pt

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000100057&tlng=pt

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