A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland

A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland

Background: Rats exposed to chronic predator scent stress mimic the phenotype of complex post-traumatic stress disorder (PTSD) in humans, including altered adrenal morphology and function. High- and low-anxiety phenotypes have been described in rats exposed to predator scent stress (PSS). This study...

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Bibliographic Details
Main Authors: Vadim Tseilikman, Maria Komelkova, Marina V. Kondashevskaya, Eugenia Manukhina, H. Fred Downey, Valerii Chereshnev, Margarita Chereshneva, Pavel Platkovskii, Anna Goryacheva, Anton Pashkov, Julia Fedotova, Olga Tseilikman, Natalya Maltseva, Olga Cherkasova, Charlotte Steenblock, Stefan R. Bornstein, Barbara Ettrich, George P. Chrousos, Enrico Ullmann
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
CPTSD
glucocorticoids
adrenal gland
behavior
Online Access:https://www.mdpi.com/1422-0067/22/24/13235

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https://www.mdpi.com/1422-0067/22/24/13235

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