Response Variability to Drug Testing in Two Models of Chemically Induced Colitis

Response Variability to Drug Testing in Two Models of Chemically Induced Colitis

The lack of knowledge regarding the pathogenesis of IBD is a challenge for the development of more effective and safer therapies. Although in vivo preclinical approaches are critical for drug testing, none of the existing models accurately reproduce human IBD. Factors that influence the intra-indivi...

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Bibliographic Details
Main Authors: Roger Suau, Anna Garcia, Carla Bernal, Mariona Llaves, Katharina Schiering, Eva Jou-Ollé, Alex Pertegaz, Arce Garcia-Jaraquemada, Ramon Bartolí, Violeta Lorén, Patri Vergara, Míriam Mañosa, Eugeni Domènech, Josep Manyé
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
inflammatory bowel disease
Crohn’s disease
ulcerative colitis
TNBS-induced colitis
DSS-induced colitis
bioluminescence
Online Access:https://www.mdpi.com/1422-0067/24/7/6424

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https://www.mdpi.com/1422-0067/24/7/6424

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