Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells

Dectin-1 Controls TSLP-Induced Th2 Response by Regulating STAT3, STAT6, and p50-RelB Activities in Dendritic Cells

The epithelium-associated cytokine thymic stromal lymphopoietin (TSLP) can induce OX40L and CCL17 expression by myeloid dendritic cells (mDCs), which contributes to aberrant Th2-type immune responses. Herein, we report that such TSLP-induced Th2-type immune response can be effectively controlled by...

Повний опис

Бібліографічні деталі
Автори: Chao Gu, Katherine Upchurch, Joshua Horton, Mathew Wiest, Sandra Zurawski, Mark Millard, Robert R. Kane, HyeMee Joo, Lisa A. Miller, SangKon Oh
Формат: Стаття
Мова:English
Опубліковано: Frontiers Media S.A. 2021-07-01
Серія:Frontiers in Immunology
Предмети:
Dectin-1
TSLP
OX40L
dendritic cells
STAT3
STAT6
Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fimmu.2021.678036/full

Інтернет

https://www.frontiersin.org/articles/10.3389/fimmu.2021.678036/full

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