Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight.

Low birth weight (LBW) is associated with increased future risk of insulin resistance and type 2 diabetes mellitus. The underlying molecular mechanisms remain poorly understood. We have previously shown that young LBW men have reduced skeletal muscle expression of PI3K p85alpha regulatory subunit an...

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Bibliographic Details
Main Authors: Christine B Jensen, Malgorzata S Martin-Gronert, Heidi Storgaard, Sten Madsbad, Allan Vaag, Susan E Ozanne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2580025?pdf=render