Differential immunological effects of silica nanoparticles on peripheral blood mononuclear cells of silicosis patients and controls

Silicosis is a fibrotic disease caused by the inhalation of respirable silica particles, which are typically engulfed by alveolar macrophages and subsequently induce the release of inflammatory cytokines. Various animal experimental and human studies have focused on modeling silicosis, to assess the...

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Bibliographic Details
Main Authors: Nirosha Ganesan, Steven Ronsmans, Peter Hoet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1025028/full