Liposome-based Formulation for Intracellular Delivery of Functional Proteins

Liposome-based Formulation for Intracellular Delivery of Functional Proteins

The intracellular delivery of biologically active protein represents an important emerging strategy for both fundamental and therapeutic applications. Here, we optimized in vitro delivery of two functional proteins, the β-galactosidase (β-gal) enzyme and the anti-cytokeratin8 (K8) antibody, using li...

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Bibliographic Details
Main Authors: Benoît Chatin, Mathieu Mével, Julie Devallière, Laurence Dallet, Thomas Haudebourg, Pauline Peuziat, Thibault Colombani, Mathieu Berchel, Olivier Lambert, Aleksander Edelman, Bruno Pitard
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
antibody delivery
ionizable lipids
intracellular delivery
supramolecular assembly
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300294

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http://www.sciencedirect.com/science/article/pii/S2162253116300294

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