Computer-Aided Design of Antimicrobial Peptides: Are We Generating Effective Drug Candidates?

Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally occurring and synthetic AMPs have shown promising results against a series of clinically relevant bacteria. Even so, this class o...

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Bibliographic Details
Main Authors: Marlon H. Cardoso, Raquel Q. Orozco, Samilla B. Rezende, Gisele Rodrigues, Karen G. N. Oshiro, Elizabete S. Cândido, Octávio L. Franco
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.03097/full